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H2B1L rabbit pAb
商品貨號(hào): PLA021050
適 應(yīng) 性: 人,大鼠,小鼠,
WB
¥600元
規(guī)格:
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MSDS
說明書
商品描述
  • 基因名稱: HIST1H2BL H2BFC
  • 蛋白名稱: H2B1L
  • Human_gene_id: 8340
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8340
  • Human_swiss_prot_no: Q99880
  • Human_swiss_link: https://www.uniprot.org/uniprotkb/Q99880/entry
  • 特異性: This antibody detects endogenous levels of H2B1L at Human
  • 組成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來源: Polyclonal, Rabbit,IgG
  • 稀釋: WB 1:500-2000
  • 純化工藝: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度: 1 mg/ml
  • 儲(chǔ)存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書: 1
  • Msds: MSDS_Antibody.pdf
  • 分子量: 14kD
  • 功能: function:Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.,PTM:Monoubiquitination of Lys-121 by the RNF20/40 complex gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation. It also functions cooperatively with the FACT dimer to stimulate elongation by RNA polymerase II.,PTM:Phosphorylated on Ser-15 by STK4/MST1 during apoptosis; which facilitates apoptotic chromatin condensation. Also phosphorylated on Ser-15 in response to DNA double strand breaks (DSBs), and in correlation with somatic hypermutation and immunoglobulin class-switch recombination.,similarity:Belongs to the histone H2B family.,subunit:The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.,
  • 相關(guān)產(chǎn)品: RS0001,RS0002,YM3028,YM3029
  • 細(xì)胞定位: Nucleus. Chromosome.
  • 科研貨號(hào): PLA021050
H2B1L rabbit pAb
Catalog No PLA021050
Product information
  • 基因名稱: HIST1H2BL H2BFC
  • 蛋白名稱: H2B1L
  • Human_gene_id: 8340
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8340
  • Human_swiss_prot_no: Q99880
  • Human_swiss_link: https://www.uniprot.org/uniprotkb/Q99880/entry
  • 特異性: This antibody detects endogenous levels of H2B1L at Human
  • 組成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來源: Polyclonal, Rabbit,IgG
  • 稀釋: WB 1:500-2000
  • 純化工藝: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度: 1 mg/ml
  • 儲(chǔ)存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書: 1
  • Msds: MSDS_Antibody.pdf
  • 分子量: 14kD
  • 功能: function:Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.,PTM:Monoubiquitination of Lys-121 by the RNF20/40 complex gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation. It also functions cooperatively with the FACT dimer to stimulate elongation by RNA polymerase II.,PTM:Phosphorylated on Ser-15 by STK4/MST1 during apoptosis; which facilitates apoptotic chromatin condensation. Also phosphorylated on Ser-15 in response to DNA double strand breaks (DSBs), and in correlation with somatic hypermutation and immunoglobulin class-switch recombination.,similarity:Belongs to the histone H2B family.,subunit:The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.,
  • 相關(guān)產(chǎn)品: RS0001,RS0002,YM3028,YM3029
  • 細(xì)胞定位: Nucleus. Chromosome.
  • 科研貨號(hào): PLA021050
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.zjgzfxx.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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