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RIP140 rabbit pAb
商品貨號(hào)： PLA021326
適 應(yīng) 性： 人,小鼠,大鼠
WB IHC ELISA
￥600元
規(guī)格：
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MSDS
說(shuō)明書(shū)
商品描述
  • 基因名稱： NRIP1
  • 蛋白名稱： RIP140
  • Human_gene_id： 8204
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8204
  • Human_swiss_prot_no： P48552
  • Human_swiss_link： https://www.uniprot.org/uniprotkb/P48552/entry
  • Mouse_gene_id： 268903
  • Mouse_gene_link： https://www.uniprot.org/uniprot/268903
  • Mouse_swiss_prot_no： Q8CBD1
  • Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q8CBD1
  • 特異性： This antibody detects endogenous levels of Human,Mouse,Rat RIP140
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來(lái)源： Polyclonal, Rabbit,IgG
  • 稀釋?zhuān)? WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
  • 純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度： 1 mg/ml
  • 儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說(shuō)明書(shū)： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱： Nuclear receptor-interacting protein 1 (Nuclear factor RIP140;Receptor-interacting protein 140)
  • 分子量： 127kD
  • 功能： disease:Genetic variation in NRIP1 may act as predisposing factor for endometriosis.,domain:Contains 9 Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs, which have different affinities for nuclear receptors. The C-terminal LTKTNPILYYMLQK motif is required for ligand-dependent interaction with RAAR and RXRB homo- and heterodimers, for the corepressor activity, and for the formation of an HDAC3 complex with RARA/RXRB (By similarity). Contains at least four autonomous repression domains (RD1-4). RD1 functions via a histone deacetylase (HDAC)-independent mechanism, whereas RD2, RD3 and RD4 can function by HDAC-dependent or independent mechanisms, depending on cell type. RD2 is dependent on CTBP binding.,function:Modulates transcriptional activation by steroid receptors such as NR3C1, NR3C2 and ESR1. Also modulates transcriptional repression by nuclear hormone receptors.,PTM:Acetylation regulates its nuclear translocation and corepressive activity (By similarity). Acetylation abolishes interaction with CTBP1. Phosphorylation enhances interaction with YWHAH.,subcellular location:Localized to discrete foci and redistributes to larger nuclear domains upon binding to ligand-bound NR3C1.,subunit:Interacts with the ligand binding domain (LBD) of NR2C1 in the absence of ligand. Interacts with RARA and RXRB homodimers and RARA/RXRB heterodimers in the presence of ligand. Interacts with HDAC1 and HDAC3 via its N-terminal domain (By similarity). Interacts with CTBP1, CTBP2, ESR1, HDAC1, HDAC2, HDAC5, HDAC6, NR3C1, NR3C2, YWHAH, JUN and FOS. Found in a complex with both NR3C1 and YWHAH.,
  • 相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3341
  • 細(xì)胞定位： Nucleus . Localized to discrete foci and redistributes to larger nuclear domains upon binding to ligand-bound NR3C1.
  • 科研貨號(hào)： PLA021326
RIP140 rabbit pAb
Catalog No PLA021326
Product information
  • 基因名稱： NRIP1
  • 蛋白名稱： RIP140
  • Human_gene_id： 8204
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8204
  • Human_swiss_prot_no： P48552
  • Human_swiss_link： https://www.uniprot.org/uniprotkb/P48552/entry
  • Mouse_gene_id： 268903
  • Mouse_gene_link： https://www.uniprot.org/uniprot/268903
  • Mouse_swiss_prot_no： Q8CBD1
  • Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q8CBD1
  • 特異性： This antibody detects endogenous levels of Human,Mouse,Rat RIP140
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來(lái)源： Polyclonal, Rabbit,IgG
  • 稀釋?zhuān)? WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
  • 純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度： 1 mg/ml
  • 儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說(shuō)明書(shū)： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱： Nuclear receptor-interacting protein 1 (Nuclear factor RIP140;Receptor-interacting protein 140)
  • 分子量： 127kD
  • 功能： disease:Genetic variation in NRIP1 may act as predisposing factor for endometriosis.,domain:Contains 9 Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs, which have different affinities for nuclear receptors. The C-terminal LTKTNPILYYMLQK motif is required for ligand-dependent interaction with RAAR and RXRB homo- and heterodimers, for the corepressor activity, and for the formation of an HDAC3 complex with RARA/RXRB (By similarity). Contains at least four autonomous repression domains (RD1-4). RD1 functions via a histone deacetylase (HDAC)-independent mechanism, whereas RD2, RD3 and RD4 can function by HDAC-dependent or independent mechanisms, depending on cell type. RD2 is dependent on CTBP binding.,function:Modulates transcriptional activation by steroid receptors such as NR3C1, NR3C2 and ESR1. Also modulates transcriptional repression by nuclear hormone receptors.,PTM:Acetylation regulates its nuclear translocation and corepressive activity (By similarity). Acetylation abolishes interaction with CTBP1. Phosphorylation enhances interaction with YWHAH.,subcellular location:Localized to discrete foci and redistributes to larger nuclear domains upon binding to ligand-bound NR3C1.,subunit:Interacts with the ligand binding domain (LBD) of NR2C1 in the absence of ligand. Interacts with RARA and RXRB homodimers and RARA/RXRB heterodimers in the presence of ligand. Interacts with HDAC1 and HDAC3 via its N-terminal domain (By similarity). Interacts with CTBP1, CTBP2, ESR1, HDAC1, HDAC2, HDAC5, HDAC6, NR3C1, NR3C2, YWHAH, JUN and FOS. Found in a complex with both NR3C1 and YWHAH.,
  • 相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3341
  • 細(xì)胞定位： Nucleus . Localized to discrete foci and redistributes to larger nuclear domains upon binding to ligand-bound NR3C1.
  • 科研貨號(hào)： PLA021326
    • Hunan UPT Biotechnology Co.,Ltd
    Website：www.zjgzfxx.com Servive hotline :4006916686
    E-mail：service@uptbio.com
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