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DLG4 rabbit pAb
商品貨號(hào)： PLA021435
適 應(yīng) 性： 人,小鼠,大鼠
WB ELISA
￥600元
規(guī)格：
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MSDS
說(shuō)明書
商品描述
  • 基因名稱： DLG4 PSD95
  • 蛋白名稱： DLG4
  • Human_gene_id： 1742
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1742
  • Human_swiss_prot_no： P78352
  • Human_swiss_link： https://www.uniprot.org/uniprotkb/P78352/entry
  • Mouse_gene_id： 13385
  • Mouse_gene_link： https://www.uniprot.org/uniprot/13385
  • Mouse_swiss_prot_no： Q62108
  • Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q62108
  • Rat_gene_id： 29495
  • Rat_gene_link： https://www.uniprot.org/uniprot/29495
  • Rat_swiss_prot_no： P31016
  • Rat_swiss_link： https://www.uniprot.org/uniprotkb/P31016
  • 特異性： This antibody detects endogenous levels of Human,Mouse,Rat DLG4
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來(lái)源： Polyclonal, Rabbit,IgG
  • 稀釋： WB 1:1000-2000 ELISA 1:5000-20000
  • 純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度： 1 mg/ml
  • 儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說(shuō)明書： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱： Disks large homolog 4 (Postsynaptic density protein 95;PSD-95;Synapse-associated protein 90;SAP-90;SAP90)
  • 分子量： 80kD
  • 功能： domain:The L27 domain near the N-terminus of isoform 2 is required for HGS/HRS-dependent targeting to post-synaptic density.,domain:The PDZ domain 3 mediates interaction with ADR1B.,function:Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ACCN3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B.,PTM:Palmitoylation of isoform 1 is required for targeting to postsynaptic density.,similarity:Belongs to the MAGUK family.,similarity:Contains 1 guanylate kinase-like domain.,similarity:Contains 1 SH3 domain.,similarity:Contains 2 PDZ (DHR) domains.,similarity:Contains 3 PDZ (DHR) domains.,subcellular location:High levels in postsynaptic density of neurons in the forebrain. Also in presynaptic region of inhibitory synapses formed by cerebellar basket cells on axon hillocks of Purkinje cells.,subunit:Interacts with ANKS1B and PRR7 (By similarity). Interacts through its first two PDZ domains with GRIN2A, GRIN2B, GRIN2C, GRIN2D, ACCN3, certain splice forms of GRIN1, KCND2, CXADR and SYNGAP1. Interacts through its second PDZ domain with the PDZ domain of NOS1 or the C-terminus of CAPON. May interact with HTR2A. Interacts through its guanylate kinase-like domain with DLGAP1/GKAP, DLGAP2, DLGAP3, DLGAP4, MAP1A and BEGAIN. Interacts through its third PDZ domain with CRIPT (By similarity). Interacts through its first two PDZ domains with KCNA1, KCNA2, KCNA3, KCNA4 and ERBB4. Interacts through its first PDZ domain with GRIK2, KCNA4 and CRIPT. Interacts through its third PDZ domain with NLGN1, and probably with NLGN2 and NLGN3. Interacts through its guanylate kinase-like domain with KIF13B. Isoform 2 interacts through an L27 domain with HGS/HRS and the first L27 domain of CASK. Interacts with LRFN1.,tissue specificity:Brain.,
  • 相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3494
  • 細(xì)胞定位： Cell membrane ; Lipid-anchor ; Cytoplasmic side . Cell junction, synapse, postsynaptic density . Cell junction, synapse . Cytoplasm . Cell projection, axon . Cell projection, dendritic spine . Cell projection, dendrite . Cell junction, synapse, presynapse . High levels in postsynaptic density of neurons in the forebrain. Also in presynaptic region of inhibitory synapses formed by cerebellar basket cells on axon hillocks of Purkinje cells. Suppression of neuronal activity induces synaptic accumulation and clustering of DLG4. .
  • 組織表達(dá)： Brain.
  • tag： hot
  • 科研貨號(hào)： PLA021435
DLG4 rabbit pAb
Catalog No PLA021435
Product information
  • 基因名稱： DLG4 PSD95
  • 蛋白名稱： DLG4
  • Human_gene_id： 1742
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1742
  • Human_swiss_prot_no： P78352
  • Human_swiss_link： https://www.uniprot.org/uniprotkb/P78352/entry
  • Mouse_gene_id： 13385
  • Mouse_gene_link： https://www.uniprot.org/uniprot/13385
  • Mouse_swiss_prot_no： Q62108
  • Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q62108
  • Rat_gene_id： 29495
  • Rat_gene_link： https://www.uniprot.org/uniprot/29495
  • Rat_swiss_prot_no： P31016
  • Rat_swiss_link： https://www.uniprot.org/uniprotkb/P31016
  • 特異性： This antibody detects endogenous levels of Human,Mouse,Rat DLG4
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來(lái)源： Polyclonal, Rabbit,IgG
  • 稀釋： WB 1:1000-2000 ELISA 1:5000-20000
  • 純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度： 1 mg/ml
  • 儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說(shuō)明書： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱： Disks large homolog 4 (Postsynaptic density protein 95;PSD-95;Synapse-associated protein 90;SAP-90;SAP90)
  • 分子量： 80kD
  • 功能： domain:The L27 domain near the N-terminus of isoform 2 is required for HGS/HRS-dependent targeting to post-synaptic density.,domain:The PDZ domain 3 mediates interaction with ADR1B.,function:Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ACCN3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B.,PTM:Palmitoylation of isoform 1 is required for targeting to postsynaptic density.,similarity:Belongs to the MAGUK family.,similarity:Contains 1 guanylate kinase-like domain.,similarity:Contains 1 SH3 domain.,similarity:Contains 2 PDZ (DHR) domains.,similarity:Contains 3 PDZ (DHR) domains.,subcellular location:High levels in postsynaptic density of neurons in the forebrain. Also in presynaptic region of inhibitory synapses formed by cerebellar basket cells on axon hillocks of Purkinje cells.,subunit:Interacts with ANKS1B and PRR7 (By similarity). Interacts through its first two PDZ domains with GRIN2A, GRIN2B, GRIN2C, GRIN2D, ACCN3, certain splice forms of GRIN1, KCND2, CXADR and SYNGAP1. Interacts through its second PDZ domain with the PDZ domain of NOS1 or the C-terminus of CAPON. May interact with HTR2A. Interacts through its guanylate kinase-like domain with DLGAP1/GKAP, DLGAP2, DLGAP3, DLGAP4, MAP1A and BEGAIN. Interacts through its third PDZ domain with CRIPT (By similarity). Interacts through its first two PDZ domains with KCNA1, KCNA2, KCNA3, KCNA4 and ERBB4. Interacts through its first PDZ domain with GRIK2, KCNA4 and CRIPT. Interacts through its third PDZ domain with NLGN1, and probably with NLGN2 and NLGN3. Interacts through its guanylate kinase-like domain with KIF13B. Isoform 2 interacts through an L27 domain with HGS/HRS and the first L27 domain of CASK. Interacts with LRFN1.,tissue specificity:Brain.,
  • 相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3494
  • 細(xì)胞定位： Cell membrane ; Lipid-anchor ; Cytoplasmic side . Cell junction, synapse, postsynaptic density . Cell junction, synapse . Cytoplasm . Cell projection, axon . Cell projection, dendritic spine . Cell projection, dendrite . Cell junction, synapse, presynapse . High levels in postsynaptic density of neurons in the forebrain. Also in presynaptic region of inhibitory synapses formed by cerebellar basket cells on axon hillocks of Purkinje cells. Suppression of neuronal activity induces synaptic accumulation and clustering of DLG4. .
  • 組織表達(dá)： Brain.
  • tag： hot
  • 科研貨號(hào)： PLA021435
    • Hunan UPT Biotechnology Co.,Ltd
    Website：www.zjgzfxx.com Servive hotline :4006916686
    E-mail：service@uptbio.com
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