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首頁 > 抗體 > 兔單抗 > IGF1R (Phospho Tyr1135/1136)/Insulin Receptor β (Phospho Tyr1150/1151) Rabbit mAb
IGF1R (Phospho Tyr1135/1136)/Insulin Receptor β (Phospho Tyr1150/1151) Rabbit mAb
商品貨號： PRM8007
適 應 性： 人,小鼠,大鼠
WB IF ELISA IP
￥7000元
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商品描述
  • 發貨日期： 現貨
  • 靶點-Target： IGF IR
  • 反應性-Reactivity： 人,小鼠,大鼠
  • 應用-Applications： WB,IF,IP,ELISA
  • MW(Calculated)： 156kD
  • MW(Observed)： 95kD
  • 宿主物種-Host Species： Rabbit
  • 同種型-Isotype： IgG,Kappa
  • 偶聯-Conjugate： Phospho
  • 修飾-Modification： Tyr1135/1136/Tyr1150/1151
  • 推薦稀釋比： WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
  • 組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • 純化工藝： Protein A
  • 儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 克隆性： Monoclonal
  • 克隆號： PT0867R
  • 特異性： Antibody detects endogenous levels of IGF-I receptor and insulin receptor only when phosphorylated at tyrosine 1135/1136 or tyrosine 1150/1151, respectively. The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites): MAyLN
  • 基因名稱： IGF1R
  • 蛋白名稱： Insulin-like growth factor 1 receptor
  • 別名： IGF1R;Insulin-like growth factor 1 receptor;Insulin-like growth factor I receptor;IGF-I receptor;CD antigen CD221;INSR;Insulin receptor;IR;CD antigen CD220
  • Organism-1： Human
  • 基因ID-1： 3480;3643
  • SwissProt-1： P06213;P08069
  • Organism-2： Mouse
  • 基因ID-2： 16001;16337
  • Organism-3： Rat
  • 基因ID-3： 25718
  • SwissProt-3： P24062;P15127
  • 背景： This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014],
  • 細胞定位： Cell membrane ; Single-pass type I membrane protein .
IGF1R (Phospho Tyr1135/1136)/Insulin Receptor β (Phospho Tyr1150/1151) Rabbit mAb
Catalog No PRM8007
Product information
  • 發貨日期： 現貨
  • 靶點-Target： IGF IR
  • 反應性-Reactivity： 人,小鼠,大鼠
  • 應用-Applications： WB,IF,IP,ELISA
  • MW(Calculated)： 156kD
  • MW(Observed)： 95kD
  • 宿主物種-Host Species： Rabbit
  • 同種型-Isotype： IgG,Kappa
  • 偶聯-Conjugate： Phospho
  • 修飾-Modification： Tyr1135/1136/Tyr1150/1151
  • 推薦稀釋比： WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
  • 組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • 純化工藝： Protein A
  • 儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 克隆性： Monoclonal
  • 克隆號： PT0867R
  • 特異性： Antibody detects endogenous levels of IGF-I receptor and insulin receptor only when phosphorylated at tyrosine 1135/1136 or tyrosine 1150/1151, respectively. The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites): MAyLN
  • 基因名稱： IGF1R
  • 蛋白名稱： Insulin-like growth factor 1 receptor
  • 別名： IGF1R;Insulin-like growth factor 1 receptor;Insulin-like growth factor I receptor;IGF-I receptor;CD antigen CD221;INSR;Insulin receptor;IR;CD antigen CD220
  • Organism-1： Human
  • 基因ID-1： 3480;3643
  • SwissProt-1： P06213;P08069
  • Organism-2： Mouse
  • 基因ID-2： 16001;16337
  • Organism-3： Rat
  • 基因ID-3： 25718
  • SwissProt-3： P24062;P15127
  • 背景： This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014],
  • 細胞定位： Cell membrane ; Single-pass type I membrane protein .
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