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Doublecortin Rabbit mAb
商品貨號： PRM8008
適 應 性： 人,小鼠,大鼠
WB IHC IF ELISA IP
￥7000元
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商品描述
  • 發(fā)貨日期： 現貨
  • 靶點-Target： Doublecortin
  • 反應性-Reactivity： 人,小鼠,大鼠
  • 應用-Applications： WB,IHC,IF,IP,ELISA
  • MW(Calculated)： 41kD
  • MW(Observed)： 41kD
  • 宿主物種-Host Species： Rabbit
  • 同種型-Isotype： IgG,Kappa
  • 偶聯(lián)-Conjugate： Unmodified
  • 推薦稀釋比： IHC 1:50-1:200;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
  • 組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • 純化工藝： Protein A
  • 儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 克隆性： Monoclonal
  • 克隆號： PT0871R
  • 特異性： Endogenous
  • 基因名稱： DCX
  • 蛋白名稱： Neuronal migration protein doublecortin
  • 別名： DCX;DBCN;LISX;Neuronal migration protein doublecortin;Doublin;Lissencephalin-X;Lis-X
  • Organism-1： Human
  • 基因ID-1： 1641
  • SwissProt-1： O43602
  • Organism-2： Mouse
  • 基因ID-2： 13193
  • SwissProt-2： O88809
  • Organism-3： Rat
  • SwissProt-3： Q9ESI7
  • 背景： This gene encodes a member of the doublecortin family. The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains, which bind microtubules. In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The encoded protein appears to direct neuronal migration by regulating the organization and stability of microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene cause abnormal migration of neurons during development and disrupt the layering of the cortex, leading to epilepsy, mental retardation, subcortical band heterotopia ("double cortex" syndrome) in females and lissencephaly ("smooth brain&quo
  • 細胞定位： Cytoplasm . Cell projection, neuron projection . Localizes at neurite tips. .
Doublecortin Rabbit mAb
Catalog No PRM8008
Product information
  • 發(fā)貨日期： 現貨
  • 靶點-Target： Doublecortin
  • 反應性-Reactivity： 人,小鼠,大鼠
  • 應用-Applications： WB,IHC,IF,IP,ELISA
  • MW(Calculated)： 41kD
  • MW(Observed)： 41kD
  • 宿主物種-Host Species： Rabbit
  • 同種型-Isotype： IgG,Kappa
  • 偶聯(lián)-Conjugate： Unmodified
  • 推薦稀釋比： IHC 1:50-1:200;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
  • 組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • 純化工藝： Protein A
  • 儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 克隆性： Monoclonal
  • 克隆號： PT0871R
  • 特異性： Endogenous
  • 基因名稱： DCX
  • 蛋白名稱： Neuronal migration protein doublecortin
  • 別名： DCX;DBCN;LISX;Neuronal migration protein doublecortin;Doublin;Lissencephalin-X;Lis-X
  • Organism-1： Human
  • 基因ID-1： 1641
  • SwissProt-1： O43602
  • Organism-2： Mouse
  • 基因ID-2： 13193
  • SwissProt-2： O88809
  • Organism-3： Rat
  • SwissProt-3： Q9ESI7
  • 背景： This gene encodes a member of the doublecortin family. The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains, which bind microtubules. In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The encoded protein appears to direct neuronal migration by regulating the organization and stability of microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene cause abnormal migration of neurons during development and disrupt the layering of the cortex, leading to epilepsy, mental retardation, subcortical band heterotopia ("double cortex" syndrome) in females and lissencephaly ("smooth brain&quo
  • 細胞定位： Cytoplasm . Cell projection, neuron projection . Localizes at neurite tips. .
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