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PYK2 Rabbit mAb
商品貨號： PRM8076
適 應(yīng) 性： 人,小鼠,大鼠
WB IHC IF ELISA IP
￥800元
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商品描述
  • 發(fā)貨日期： 現(xiàn)貨
  • 靶點-Target： PYK2
  • 反應(yīng)性-Reactivity： 人,小鼠,大鼠
  • 應(yīng)用-Applications： WB,IHC,IF,IP,ELISA
  • MW(Calculated)： 116kD
  • MW(Observed)： 116kD
  • 宿主物種-Host Species： Rabbit
  • 同種型-Isotype： IgG,Kappa
  • 偶聯(lián)-Conjugate： Unmodified
  • 推薦稀釋比： IHC 1:1000-1:4000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
  • 組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • 純化工藝： Protein A
  • 儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 克隆性： Monoclonal
  • 克隆號： PT0144R
  • 特異性： Endogenous
  • 基因名稱： PTK2B
  • 蛋白名稱： Protein-tyrosine kinase 2-beta
  • 別名： PTK2B;FAK2;PYK2;RAFTK;Protein-tyrosine kinase 2-beta;Calcium-dependent tyrosine kinase;CADTK;Calcium-regulated non-receptor proline-rich tyrosine kinase;Cell adhesion kinase beta;CAK-beta;CAKB;Focal adhesion kinase 2;FADK 2;Pro
  • Organism-1： Human
  • 基因ID-1： 2185
  • SwissProt-1： Q14289
  • Organism-2： Mouse
  • 基因ID-2： 19229
  • SwissProt-2： Q9QVP9
  • Organism-3： Rat
  • 基因ID-3： 50646
  • SwissProt-3： P70600
  • 背景： This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity t
  • 細胞定位： Cytoplasm. Cytoplasm, perinuclear region. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction, focal adhesion. Cell projection, lamellipodium. Cytoplasm, cell cortex. Nucleus. Interaction with NPHP1 induces the membrane-association of the kinase. Colocalizes with integrins at the cell periphery.
PYK2 Rabbit mAb
Catalog No PRM8076
Product information
  • 發(fā)貨日期： 現(xiàn)貨
  • 靶點-Target： PYK2
  • 反應(yīng)性-Reactivity： 人,小鼠,大鼠
  • 應(yīng)用-Applications： WB,IHC,IF,IP,ELISA
  • MW(Calculated)： 116kD
  • MW(Observed)： 116kD
  • 宿主物種-Host Species： Rabbit
  • 同種型-Isotype： IgG,Kappa
  • 偶聯(lián)-Conjugate： Unmodified
  • 推薦稀釋比： IHC 1:1000-1:4000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
  • 組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • 純化工藝： Protein A
  • 儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 克隆性： Monoclonal
  • 克隆號： PT0144R
  • 特異性： Endogenous
  • 基因名稱： PTK2B
  • 蛋白名稱： Protein-tyrosine kinase 2-beta
  • 別名： PTK2B;FAK2;PYK2;RAFTK;Protein-tyrosine kinase 2-beta;Calcium-dependent tyrosine kinase;CADTK;Calcium-regulated non-receptor proline-rich tyrosine kinase;Cell adhesion kinase beta;CAK-beta;CAKB;Focal adhesion kinase 2;FADK 2;Pro
  • Organism-1： Human
  • 基因ID-1： 2185
  • SwissProt-1： Q14289
  • Organism-2： Mouse
  • 基因ID-2： 19229
  • SwissProt-2： Q9QVP9
  • Organism-3： Rat
  • 基因ID-3： 50646
  • SwissProt-3： P70600
  • 背景： This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity t
  • 細胞定位： Cytoplasm. Cytoplasm, perinuclear region. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction, focal adhesion. Cell projection, lamellipodium. Cytoplasm, cell cortex. Nucleus. Interaction with NPHP1 induces the membrane-association of the kinase. Colocalizes with integrins at the cell periphery.
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