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Met (Phospho Tyr1234/1235) Rabbit mAb
商品貨號： PRM8092
適 應 性： 人,小鼠,大鼠
WB IHC IF ELISA IP
￥7000元
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商品描述
  • 發貨日期： 現貨
  • 靶點-Target： Met
  • 反應性-Reactivity： 人,小鼠,大鼠
  • 應用-Applications： WB,IHC,IF,IP,ELISA
  • MW(Calculated)： 155kD
  • MW(Observed)： 155kD
  • 宿主物種-Host Species： Rabbit
  • 同種型-Isotype： IgG,Kappa
  • 偶聯-Conjugate： Phospho
  • 修飾-Modification： Tyr1234/1235
  • 推薦稀釋比： IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
  • 組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • 純化工藝： Protein A
  • 儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 克隆性： Monoclonal
  • 克隆號： PT0745R
  • 特異性： This antibody detects endogenous levels of Met only when phosphorylated at Tyr1234 or Thr1235,and dually phosphorylated at two sites.
  • 基因名稱： MET
  • 蛋白名稱： Met (Tyr1234/1235)
  • 別名： Hepatocyte growth factor receptor;HGF receptor;HGF/SF receptor;Proto-oncogene c-Met;Scatter factor receptor;SF receptor;Tyrosine-protein kinase Met;
  • Organism-1： Human
  • 基因ID-1： 4233
  • SwissProt-1： P08581
  • Organism-2： Mouse
  • SwissProt-2： P16056
  • Organism-3： Rat
  • 基因ID-3： 24553
  • SwissProt-3： P97523
  • 背景： This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma, hepatocellular carcinoma, and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers. [provided by RefSeq, May 2016],
  • 細胞定位： Membrane; Single-pass type I membrane protein.; [Isoform 3]: Secreted.
Met (Phospho Tyr1234/1235) Rabbit mAb
Catalog No PRM8092
Product information
  • 發貨日期： 現貨
  • 靶點-Target： Met
  • 反應性-Reactivity： 人,小鼠,大鼠
  • 應用-Applications： WB,IHC,IF,IP,ELISA
  • MW(Calculated)： 155kD
  • MW(Observed)： 155kD
  • 宿主物種-Host Species： Rabbit
  • 同種型-Isotype： IgG,Kappa
  • 偶聯-Conjugate： Phospho
  • 修飾-Modification： Tyr1234/1235
  • 推薦稀釋比： IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
  • 組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • 純化工藝： Protein A
  • 儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 克隆性： Monoclonal
  • 克隆號： PT0745R
  • 特異性： This antibody detects endogenous levels of Met only when phosphorylated at Tyr1234 or Thr1235,and dually phosphorylated at two sites.
  • 基因名稱： MET
  • 蛋白名稱： Met (Tyr1234/1235)
  • 別名： Hepatocyte growth factor receptor;HGF receptor;HGF/SF receptor;Proto-oncogene c-Met;Scatter factor receptor;SF receptor;Tyrosine-protein kinase Met;
  • Organism-1： Human
  • 基因ID-1： 4233
  • SwissProt-1： P08581
  • Organism-2： Mouse
  • SwissProt-2： P16056
  • Organism-3： Rat
  • 基因ID-3： 24553
  • SwissProt-3： P97523
  • 背景： This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma, hepatocellular carcinoma, and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers. [provided by RefSeq, May 2016],
  • 細胞定位： Membrane; Single-pass type I membrane protein.; [Isoform 3]: Secreted.
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