儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆號： PT0623R
特異性： Endogenous
基因名稱： STAT6
蛋白名稱： Signal transducer and activator of transcription 6
別名： STAT6;Signal transducer and activator of transcription 6;IL-4 Stat
Organism-1： Human
基因ID-1： 6778
SwissProt-1： P42226
Organism-2： Mouse
基因ID-2： 20852
SwissProt-2： P52633
背景： The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010],
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆號： PT0623R
特異性： Endogenous
基因名稱： STAT6
蛋白名稱： Signal transducer and activator of transcription 6
別名： STAT6;Signal transducer and activator of transcription 6;IL-4 Stat
Organism-1： Human
基因ID-1： 6778
SwissProt-1： P42226
Organism-2： Mouse
基因ID-2： 20852
SwissProt-2： P52633
背景： The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010],
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