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Lamin A/C Rabbit mAb
商品貨號(hào)： PRM8306
適 應(yīng) 性： 人,小鼠,大鼠
WB IHC IF ELISA IP
￥800元
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商品描述
  • 發(fā)貨日期： 現(xiàn)貨
  • 靶點(diǎn)-Target： Lamin A/C (phospho Ser392)
  • 反應(yīng)性-Reactivity： 人,小鼠,大鼠
  • 應(yīng)用-Applications： WB,IHC,IF,IP,ELISA
  • MW(Calculated)： 74kD,63kD
  • MW(Observed)： 74kD,63kD
  • 宿主物種-Host Species： Rabbit
  • 同種型-Isotype： IgG,Kappa
  • 偶聯(lián)-Conjugate： Unmodified
  • 推薦稀釋比： IHC 1:1000-1:4000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
  • 組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • 純化工藝： Protein A
  • 儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 克隆性： Monoclonal
  • 克隆號(hào)： PT0401R
  • 特異性： Endogenous
  • 基因名稱： LMNA LMN1
  • 蛋白名稱： Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)]
  • 別名： Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)]
  • Organism-1： Human
  • 基因ID-1： 4000
  • SwissProt-1： P02545
  • Organism-2： Mouse
  • 基因ID-2： 16905
  • SwissProt-2： P48678
  • 背景： Lamin A/C(LMNA) Homo sapiens The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. [provided by RefSeq, Apr 2012],
  • 細(xì)胞定位： Nucleus
Lamin A/C Rabbit mAb
Catalog No PRM8306
Product information
  • 發(fā)貨日期： 現(xiàn)貨
  • 靶點(diǎn)-Target： Lamin A/C (phospho Ser392)
  • 反應(yīng)性-Reactivity： 人,小鼠,大鼠
  • 應(yīng)用-Applications： WB,IHC,IF,IP,ELISA
  • MW(Calculated)： 74kD,63kD
  • MW(Observed)： 74kD,63kD
  • 宿主物種-Host Species： Rabbit
  • 同種型-Isotype： IgG,Kappa
  • 偶聯(lián)-Conjugate： Unmodified
  • 推薦稀釋比： IHC 1:1000-1:4000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
  • 組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • 純化工藝： Protein A
  • 儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 克隆性： Monoclonal
  • 克隆號(hào)： PT0401R
  • 特異性： Endogenous
  • 基因名稱： LMNA LMN1
  • 蛋白名稱： Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)]
  • 別名： Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)]
  • Organism-1： Human
  • 基因ID-1： 4000
  • SwissProt-1： P02545
  • Organism-2： Mouse
  • 基因ID-2： 16905
  • SwissProt-2： P48678
  • 背景： Lamin A/C(LMNA) Homo sapiens The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. [provided by RefSeq, Apr 2012],
  • 細(xì)胞定位： Nucleus
    • Hunan UPT Biotechnology Co.,Ltd
    Website：www.zjgzfxx.com Servive hotline :4006916686
    E-mail：service@uptbio.com
    Address：
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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