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PRKACA Rabbit mAb
商品貨號(hào)： PRM8427
適 應(yīng) 性： 人,小鼠,大鼠
WB IHC IF ELISA IP
￥800元
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商品描述
  • 發(fā)貨日期： 現(xiàn)貨
  • 靶點(diǎn)-Target： PKA
  • 反應(yīng)性-Reactivity： 人,小鼠,大鼠
  • 應(yīng)用-Applications： WB,IHC,IF,IP,ELISA
  • MW(Calculated)： 40kD
  • MW(Observed)： 40kD
  • 宿主物種-Host Species： Rabbit
  • 同種型-Isotype： IgG,Kappa
  • 偶聯(lián)-Conjugate： Unmodified
  • 推薦稀釋比： IHC 1:2000-1:10000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
  • 組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • 純化工藝： Protein A
  • 儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 克隆性： Monoclonal
  • 克隆號(hào)： PT0438R
  • 特異性： Endogenous
  • 基因名稱： PRKACA
  • 蛋白名稱： cAMP-dependent protein kinase catalytic subunit alpha
  • 別名： PRKACA;PKACA;cAMP-dependent protein kinase catalytic subunit alpha;PKA C-alpha
  • Organism-1： Human
  • 基因ID-1： 5566
  • SwissProt-1： P17612
  • Organism-2： Mouse
  • 基因ID-2： 18747
  • SwissProt-2： P05132
  • Organism-3： Rat
  • SwissProt-3： P27791
  • 背景： This gene encodes one of the catalytic subunits of protein kinase A, which exists as a tetrameric holoenzyme with two regulatory subunits and two catalytic subunits, in its inactive form. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. cAMP-dependent phosphorylation of proteins by protein kinase A is important to many cellular processes, including differentiation, proliferation, and apoptosis. Constitutive activation of this gene caused either by somatic mutations, or genomic duplications of regions that include this gene, have been associated with hyperplasias and adenomas of the adrenal cortex and are linked to corticotropin-independent Cushing's syndrome. Altern
  • 細(xì)胞定位： Cytoplasm, Membrane
PRKACA Rabbit mAb
Catalog No PRM8427
Product information
  • 發(fā)貨日期： 現(xiàn)貨
  • 靶點(diǎn)-Target： PKA
  • 反應(yīng)性-Reactivity： 人,小鼠,大鼠
  • 應(yīng)用-Applications： WB,IHC,IF,IP,ELISA
  • MW(Calculated)： 40kD
  • MW(Observed)： 40kD
  • 宿主物種-Host Species： Rabbit
  • 同種型-Isotype： IgG,Kappa
  • 偶聯(lián)-Conjugate： Unmodified
  • 推薦稀釋比： IHC 1:2000-1:10000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
  • 組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • 純化工藝： Protein A
  • 儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 克隆性： Monoclonal
  • 克隆號(hào)： PT0438R
  • 特異性： Endogenous
  • 基因名稱： PRKACA
  • 蛋白名稱： cAMP-dependent protein kinase catalytic subunit alpha
  • 別名： PRKACA;PKACA;cAMP-dependent protein kinase catalytic subunit alpha;PKA C-alpha
  • Organism-1： Human
  • 基因ID-1： 5566
  • SwissProt-1： P17612
  • Organism-2： Mouse
  • 基因ID-2： 18747
  • SwissProt-2： P05132
  • Organism-3： Rat
  • SwissProt-3： P27791
  • 背景： This gene encodes one of the catalytic subunits of protein kinase A, which exists as a tetrameric holoenzyme with two regulatory subunits and two catalytic subunits, in its inactive form. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. cAMP-dependent phosphorylation of proteins by protein kinase A is important to many cellular processes, including differentiation, proliferation, and apoptosis. Constitutive activation of this gene caused either by somatic mutations, or genomic duplications of regions that include this gene, have been associated with hyperplasias and adenomas of the adrenal cortex and are linked to corticotropin-independent Cushing's syndrome. Altern
  • 細(xì)胞定位： Cytoplasm, Membrane
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