儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆號： PT0105R
特異性： Endogenous
基因名稱： DDIT3
蛋白名稱： DDIT3
別名： DDIT3
Organism-1： Human
基因ID-1： 1649
SwissProt-1： P35638
Organism-2： Mouse
SwissProt-2： P35639
Organism-3： Rat
SwissProt-3： Q62857
背景： This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified. [provided by RefSeq, Aug 2010],
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆號： PT0105R
特異性： Endogenous
基因名稱： DDIT3
蛋白名稱： DDIT3
別名： DDIT3
Organism-1： Human
基因ID-1： 1649
SwissProt-1： P35638
Organism-2： Mouse
SwissProt-2： P35639
Organism-3： Rat
SwissProt-3： Q62857
背景： This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified. [provided by RefSeq, Aug 2010],
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