儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆號： PT0399R
特異性： Endogenous
基因名稱： CDK4
蛋白名稱： Cyclin-dependent kinase 4
別名： CDK4;Cyclin-dependent kinase 4;Cell division protein kinase 4;PSK-J3
Organism-1： Human
基因ID-1： 1019
SwissProt-1： P11802
Organism-2： Mouse
基因ID-2： 12567
SwissProt-2： P30285
Organism-3： Rat
基因ID-3： 94201
SwissProt-3： P35426
背景： cyclin dependent kinase 4(CDK4) Homo sapiens The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported. [provided by RefSeq, Jul 2008],
儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆號： PT0399R
特異性： Endogenous
基因名稱： CDK4
蛋白名稱： Cyclin-dependent kinase 4
別名： CDK4;Cyclin-dependent kinase 4;Cell division protein kinase 4;PSK-J3
Organism-1： Human
基因ID-1： 1019
SwissProt-1： P11802
Organism-2： Mouse
基因ID-2： 12567
SwissProt-2： P30285
Organism-3： Rat
基因ID-3： 94201
SwissProt-3： P35426
背景： cyclin dependent kinase 4(CDK4) Homo sapiens The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported. [provided by RefSeq, Jul 2008],
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