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xCT Rabbit mAb
商品貨號(hào)： PRM8464
適 應(yīng) 性： 人,小鼠,大鼠
WB IHC IF ELISA IP
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  • 發(fā)貨日期： 現(xiàn)貨
  • 靶點(diǎn)-Target： SLC7A11
  • 反應(yīng)性-Reactivity： 人,小鼠,大鼠
  • 應(yīng)用-Applications： WB,IHC,IF,IP,ELISA
  • MW(Calculated)： 37kD
  • MW(Observed)： 55kD
  • 宿主物種-Host Species： Rabbit
  • 同種型-Isotype： IgG,Kappa
  • 偶聯(lián)-Conjugate： Unmodified
  • 推薦稀釋比： IHC 1:200-1:1000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200,
  • 組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • 純化工藝： Protein A
  • 儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 克隆性： Monoclonal
  • 克隆號(hào)： PT0398R
  • 特異性： Endogenous
  • 基因名稱： SLC7A11
  • 蛋白名稱： Cystine/glutamate transporter (Amino acid transport system xc-) (Calcium channel blocker resistance protein CCBR1) (Solute carrier family 7 member 11) (xCT)
  • 別名： Cystine/glutamate transporter;Amino acid transport system xc-;Calcium channel blocker resistance protein CCBR1;Solute carrier family 7 member 11;xCT;
  • Organism-1： Human
  • 基因ID-1： 23657
  • SwissProt-1： Q9UPY5
  • Organism-2： Mouse
  • 基因ID-2： 26570
  • SwissProt-2： Q9WTR6
  • 背景： This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. [provided by RefSeq, Sep 2011]
  • 細(xì)胞定位： Membrane
xCT Rabbit mAb
Catalog No PRM8464
Product information
  • 發(fā)貨日期： 現(xiàn)貨
  • 靶點(diǎn)-Target： SLC7A11
  • 反應(yīng)性-Reactivity： 人,小鼠,大鼠
  • 應(yīng)用-Applications： WB,IHC,IF,IP,ELISA
  • MW(Calculated)： 37kD
  • MW(Observed)： 55kD
  • 宿主物種-Host Species： Rabbit
  • 同種型-Isotype： IgG,Kappa
  • 偶聯(lián)-Conjugate： Unmodified
  • 推薦稀釋比： IHC 1:200-1:1000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200,
  • 組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • 純化工藝： Protein A
  • 儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 克隆性： Monoclonal
  • 克隆號(hào)： PT0398R
  • 特異性： Endogenous
  • 基因名稱： SLC7A11
  • 蛋白名稱： Cystine/glutamate transporter (Amino acid transport system xc-) (Calcium channel blocker resistance protein CCBR1) (Solute carrier family 7 member 11) (xCT)
  • 別名： Cystine/glutamate transporter;Amino acid transport system xc-;Calcium channel blocker resistance protein CCBR1;Solute carrier family 7 member 11;xCT;
  • Organism-1： Human
  • 基因ID-1： 23657
  • SwissProt-1： Q9UPY5
  • Organism-2： Mouse
  • 基因ID-2： 26570
  • SwissProt-2： Q9WTR6
  • 背景： This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. [provided by RefSeq, Sep 2011]
  • 細(xì)胞定位： Membrane
    • Hunan UPT Biotechnology Co.,Ltd
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    E-mail：service@uptbio.com
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