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Glucocorticoid Receptor Rabbit mAb
商品貨號： PRM8507
適 應(yīng) 性： 人,小鼠,大鼠
WB IHC IF ELISA IP
￥800元
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  • 發(fā)貨日期： 現(xiàn)貨
  • 靶點(diǎn)-Target： Glucocorticoid Receptor
  • 反應(yīng)性-Reactivity： 人,小鼠,大鼠
  • 應(yīng)用-Applications： WB,IHC,IF,IP,ELISA
  • MW(Calculated)： 85kD
  • MW(Observed)： 94kD
  • 宿主物種-Host Species： Rabbit
  • 同種型-Isotype： IgG,Kappa
  • 偶聯(lián)-Conjugate： Unmodified
  • 推薦稀釋比： IHC 1:1000-1:4000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200,
  • 組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • 純化工藝： Protein A
  • 儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 克隆性： Monoclonal
  • 克隆號： PT0306R
  • 特異性： Endogenous
  • 基因名稱： Nr3c1 Grl Grl1
  • 蛋白名稱： Glucocorticoid receptor (GR) (Nuclear receptor subfamily 3 group C member 1)
  • 別名： GCCR;GCR;GCR_HUMAN;GCRST;glucocorticoid nuclear receptor variant 1;Glucocorticoid receptor;GR;GRL;Grl1;nr3c1;Nuclear receptor subfamily 3 group C member 1;nuclear receptor subfamily 3, group C, member 1;glucocorticoid receptor;
  • Organism-1： Human
  • 基因ID-1： 2908
  • SwissProt-1： P04150
  • 背景： This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms. Additional isoforms resulting from the use of alternate in-frame translation initiation sites have also been described, and shown to be functional, displaying diverse cytoplasm-to-nucleus trafficking patterns and distinct transcriptional activities (PMID:15866175). [provided by RefSeq, Feb 2011]
  • 細(xì)胞定位： Nucleus
Glucocorticoid Receptor Rabbit mAb
Catalog No PRM8507
Product information
  • 發(fā)貨日期： 現(xiàn)貨
  • 靶點(diǎn)-Target： Glucocorticoid Receptor
  • 反應(yīng)性-Reactivity： 人,小鼠,大鼠
  • 應(yīng)用-Applications： WB,IHC,IF,IP,ELISA
  • MW(Calculated)： 85kD
  • MW(Observed)： 94kD
  • 宿主物種-Host Species： Rabbit
  • 同種型-Isotype： IgG,Kappa
  • 偶聯(lián)-Conjugate： Unmodified
  • 推薦稀釋比： IHC 1:1000-1:4000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200,
  • 組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • 純化工藝： Protein A
  • 儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 克隆性： Monoclonal
  • 克隆號： PT0306R
  • 特異性： Endogenous
  • 基因名稱： Nr3c1 Grl Grl1
  • 蛋白名稱： Glucocorticoid receptor (GR) (Nuclear receptor subfamily 3 group C member 1)
  • 別名： GCCR;GCR;GCR_HUMAN;GCRST;glucocorticoid nuclear receptor variant 1;Glucocorticoid receptor;GR;GRL;Grl1;nr3c1;Nuclear receptor subfamily 3 group C member 1;nuclear receptor subfamily 3, group C, member 1;glucocorticoid receptor;
  • Organism-1： Human
  • 基因ID-1： 2908
  • SwissProt-1： P04150
  • 背景： This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms. Additional isoforms resulting from the use of alternate in-frame translation initiation sites have also been described, and shown to be functional, displaying diverse cytoplasm-to-nucleus trafficking patterns and distinct transcriptional activities (PMID:15866175). [provided by RefSeq, Feb 2011]
  • 細(xì)胞定位： Nucleus
    • Hunan UPT Biotechnology Co.,Ltd
    Website：www.zjgzfxx.com Servive hotline :4006916686
    E-mail：service@uptbio.com
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