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首頁 > 抗體 > 兔單抗 > Pyruvate Dehydrogenase E1 α Rabbit mAb
Pyruvate Dehydrogenase E1 α Rabbit mAb
商品貨號： PRM8512
適 應 性： 人,小鼠,大鼠
WB IHC IF ELISA IP
￥800元
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商品描述
  • 發(fā)貨日期： 現(xiàn)貨
  • 靶點-Target： Pyruvate Dehydrogenase E1 α
  • 反應性-Reactivity： 人,小鼠,大鼠
  • 應用-Applications： WB,IHC,IF,IP,ELISA
  • MW(Calculated)： 43kD
  • MW(Observed)： 43kD
  • 宿主物種-Host Species： Rabbit
  • 同種型-Isotype： IgG,Kappa
  • 偶聯(lián)-Conjugate： Unmodified
  • 推薦稀釋比： IHC 1:200-1:1000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200,
  • 組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • 純化工藝： Protein A
  • 儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 克隆性： Monoclonal
  • 克隆號： PT0322R
  • 特異性： Endogenous
  • 基因名稱： >>Glycolysis / Gluconeogenesis;>>Citrate cycle (TCA cycle);>>Pyruvate metabolism;>>Metabolic pathways;>>Carbon metabolism;>>HIF-1 signaling pathway;>>Glucagon signaling pathway;>>Central carbon metabolism in cancer;>>Diabetic cardiomyopathy
  • 蛋白名稱： PDHA1 ODPA
  • 別名： PDHA1;PHE1A;Pyruvate dehydrogenase E1 component subunit alpha;somatic form, mitochondrial;PDHE1-A type I
  • Organism-1： Human
  • 基因ID-1： 5160
  • SwissProt-1： P08559
  • Organism-2： Mouse
  • 基因ID-2： 18597
  • SwissProt-2： P35486
  • Organism-3： Rat
  • SwissProt-3： P26284
  • 背景： The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010],
  • 細胞定位： Mitochondrion matrix
Pyruvate Dehydrogenase E1 α Rabbit mAb
Catalog No PRM8512
Product information
  • 發(fā)貨日期： 現(xiàn)貨
  • 靶點-Target： Pyruvate Dehydrogenase E1 α
  • 反應性-Reactivity： 人,小鼠,大鼠
  • 應用-Applications： WB,IHC,IF,IP,ELISA
  • MW(Calculated)： 43kD
  • MW(Observed)： 43kD
  • 宿主物種-Host Species： Rabbit
  • 同種型-Isotype： IgG,Kappa
  • 偶聯(lián)-Conjugate： Unmodified
  • 推薦稀釋比： IHC 1:200-1:1000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200,
  • 組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • 純化工藝： Protein A
  • 儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 克隆性： Monoclonal
  • 克隆號： PT0322R
  • 特異性： Endogenous
  • 基因名稱： >>Glycolysis / Gluconeogenesis;>>Citrate cycle (TCA cycle);>>Pyruvate metabolism;>>Metabolic pathways;>>Carbon metabolism;>>HIF-1 signaling pathway;>>Glucagon signaling pathway;>>Central carbon metabolism in cancer;>>Diabetic cardiomyopathy
  • 蛋白名稱： PDHA1 ODPA
  • 別名： PDHA1;PHE1A;Pyruvate dehydrogenase E1 component subunit alpha;somatic form, mitochondrial;PDHE1-A type I
  • Organism-1： Human
  • 基因ID-1： 5160
  • SwissProt-1： P08559
  • Organism-2： Mouse
  • 基因ID-2： 18597
  • SwissProt-2： P35486
  • Organism-3： Rat
  • SwissProt-3： P26284
  • 背景： The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010],
  • 細胞定位： Mitochondrion matrix
    • Hunan UPT Biotechnology Co.,Ltd
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