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Collagen IV Rabbit mAb
商品貨號(hào)： PRM8615
適 應(yīng) 性： 人,
WB IHC IF ELISA IP
￥800元
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商品描述
  • 發(fā)貨日期： 現(xiàn)貨
  • 靶點(diǎn)-Target： Collagen IV
  • 反應(yīng)性-Reactivity： 人,
  • 應(yīng)用-Applications： WB,IHC,IF,IP,ELISA
  • MW(Calculated)： 160kD
  • MW(Observed)： 200kD
  • 宿主物種-Host Species： Rabbit
  • 同種型-Isotype： IgG,Kappa
  • 偶聯(lián)-Conjugate： Unmodified
  • 推薦稀釋比： IHC 1:200-1000;WB 1:1000-5000;IF 1:200-1000;ELISA 1:5000-20000;IP 1:50-200
  • 組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • 純化工藝： Protein A
  • 儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 克隆性： Monoclonal
  • 克隆號(hào)： PT0131R
  • 特異性： Endogenous
  • 基因名稱(chēng)： COL4A1
  • 蛋白名稱(chēng)： Collagen Type IV
  • 別名： Arresten;BSVD;CO4A1_HUMAN;COL4A1;COL4A1 NC1 domain;COL4A2;COL4A3;COL4A4;COL4A5;collagen alpha-1;IV;chain;Collagen IV Alpha 1 Polypeptide;Collagen IV Alpha 2 Polypeptide;Collagen Of Basement Membrane Alpha 1 Chain;Collagen Of Basement Membrane Alpha 2 Chain;Collagen Type IV Alpha 1;collagen type IV alpha 1 chain;Collagen Type IV Alpha 2;Collagen Type IV Alpha 3;Collagen Type IV Alpha 4;Collagen Type IV Alpha 5;RatOR
  • Organism-1： Human
  • 基因ID-1： 1282
  • SwissProt-1： P02462
  • 背景： This gene encodes a type IV collagen alpha protein. Type IV collagen proteins are integral components of basement membranes. This gene shares a bidirectional promoter with a paralogous gene on the opposite strand. The protein consists of an amino-terminal 7S domain, a triple-helix forming collagenous domain, and a carboxy-terminal non-collagenous domain. It functions as part of a heterotrimer and interacts with other extracellular matrix components such as perlecans, proteoglycans, and laminins. In addition, proteolytic cleavage of the non-collagenous carboxy-terminal domain results in a biologically active fragment known as arresten, which has anti-angiogenic and tumor suppressor properties. Mutations in this gene cause porencephaly, cerebrovascular disease, and renal and muscular defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014],
  • 細(xì)胞定位： Cytoplasmic
Collagen IV Rabbit mAb
Catalog No PRM8615
Product information
  • 發(fā)貨日期： 現(xiàn)貨
  • 靶點(diǎn)-Target： Collagen IV
  • 反應(yīng)性-Reactivity： 人,
  • 應(yīng)用-Applications： WB,IHC,IF,IP,ELISA
  • MW(Calculated)： 160kD
  • MW(Observed)： 200kD
  • 宿主物種-Host Species： Rabbit
  • 同種型-Isotype： IgG,Kappa
  • 偶聯(lián)-Conjugate： Unmodified
  • 推薦稀釋比： IHC 1:200-1000;WB 1:1000-5000;IF 1:200-1000;ELISA 1:5000-20000;IP 1:50-200
  • 組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • 純化工藝： Protein A
  • 儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 克隆性： Monoclonal
  • 克隆號(hào)： PT0131R
  • 特異性： Endogenous
  • 基因名稱(chēng)： COL4A1
  • 蛋白名稱(chēng)： Collagen Type IV
  • 別名： Arresten;BSVD;CO4A1_HUMAN;COL4A1;COL4A1 NC1 domain;COL4A2;COL4A3;COL4A4;COL4A5;collagen alpha-1;IV;chain;Collagen IV Alpha 1 Polypeptide;Collagen IV Alpha 2 Polypeptide;Collagen Of Basement Membrane Alpha 1 Chain;Collagen Of Basement Membrane Alpha 2 Chain;Collagen Type IV Alpha 1;collagen type IV alpha 1 chain;Collagen Type IV Alpha 2;Collagen Type IV Alpha 3;Collagen Type IV Alpha 4;Collagen Type IV Alpha 5;RatOR
  • Organism-1： Human
  • 基因ID-1： 1282
  • SwissProt-1： P02462
  • 背景： This gene encodes a type IV collagen alpha protein. Type IV collagen proteins are integral components of basement membranes. This gene shares a bidirectional promoter with a paralogous gene on the opposite strand. The protein consists of an amino-terminal 7S domain, a triple-helix forming collagenous domain, and a carboxy-terminal non-collagenous domain. It functions as part of a heterotrimer and interacts with other extracellular matrix components such as perlecans, proteoglycans, and laminins. In addition, proteolytic cleavage of the non-collagenous carboxy-terminal domain results in a biologically active fragment known as arresten, which has anti-angiogenic and tumor suppressor properties. Mutations in this gene cause porencephaly, cerebrovascular disease, and renal and muscular defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014],
  • 細(xì)胞定位： Cytoplasmic
    • Hunan UPT Biotechnology Co.,Ltd
    Website：www.zjgzfxx.com Servive hotline :4006916686
    E-mail：service@uptbio.com
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