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PLCγ1 (Phospho Tyr783) Rabbit mAb
商品貨號： PRM8693
適 應 性： 人,小鼠,大鼠
WB IHC IF ELISA IP
￥7000元
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商品描述
  • 發貨日期： 現貨
  • 靶點-Target： PLCG1
  • 反應性-Reactivity： 人,小鼠,大鼠
  • 應用-Applications： WB,IHC,IF,IP,ELISA
  • MW(Calculated)： 149kD
  • MW(Observed)： 149kD
  • 宿主物種-Host Species： Rabbit
  • 同種型-Isotype： IgG, Kappa
  • 偶聯-Conjugate： Phospho
  • 修飾-Modification： Tyr783
  • 推薦稀釋比： IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
  • 組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • 純化工藝： Protein A
  • 儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 克隆號： PT0758R
  • 特異性： PLCγ1 (Phospho Tyr783) Monoclonal Antibody detects endogenous levels of PLC γ1 protein only when phosphorylated at Y783.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):GFyVE
  • 基因名稱： PLCG1
  • 蛋白名稱： 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
  • 別名： PLCG1;PLC1;1-phosphatidylinositol 4;5-bisphosphate phosphodiesterase gamma-1;PLC-148;Phosphoinositide phospholipase C-gamma-1;Phospholipase C-II;PLC-II;Phospholipase C-gamma-1;PLC-gamma-1
  • Organism-1： Human
  • 基因ID-1： 5335
  • SwissProt-1： P19174
  • Organism-2： Mouse
  • 基因ID-2： 18803
  • SwissProt-2： Q62077
  • Organism-3： Rat
  • 基因ID-3： 25738
  • SwissProt-3： P10686
  • 背景： The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
  • 細胞定位： Cell projection, lamellipodium . Cell projection, ruffle . Rapidly redistributed to ruffles and lamellipodia structures in response to epidermal growth factor (EGF) treatment. .
PLCγ1 (Phospho Tyr783) Rabbit mAb
Catalog No PRM8693
Product information
  • 發貨日期： 現貨
  • 靶點-Target： PLCG1
  • 反應性-Reactivity： 人,小鼠,大鼠
  • 應用-Applications： WB,IHC,IF,IP,ELISA
  • MW(Calculated)： 149kD
  • MW(Observed)： 149kD
  • 宿主物種-Host Species： Rabbit
  • 同種型-Isotype： IgG, Kappa
  • 偶聯-Conjugate： Phospho
  • 修飾-Modification： Tyr783
  • 推薦稀釋比： IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
  • 組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • 純化工藝： Protein A
  • 儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 克隆號： PT0758R
  • 特異性： PLCγ1 (Phospho Tyr783) Monoclonal Antibody detects endogenous levels of PLC γ1 protein only when phosphorylated at Y783.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):GFyVE
  • 基因名稱： PLCG1
  • 蛋白名稱： 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
  • 別名： PLCG1;PLC1;1-phosphatidylinositol 4;5-bisphosphate phosphodiesterase gamma-1;PLC-148;Phosphoinositide phospholipase C-gamma-1;Phospholipase C-II;PLC-II;Phospholipase C-gamma-1;PLC-gamma-1
  • Organism-1： Human
  • 基因ID-1： 5335
  • SwissProt-1： P19174
  • Organism-2： Mouse
  • 基因ID-2： 18803
  • SwissProt-2： Q62077
  • Organism-3： Rat
  • 基因ID-3： 25738
  • SwissProt-3： P10686
  • 背景： The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
  • 細胞定位： Cell projection, lamellipodium . Cell projection, ruffle . Rapidly redistributed to ruffles and lamellipodia structures in response to epidermal growth factor (EGF) treatment. .
    • Hunan UPT Biotechnology Co.,Ltd
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