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首頁(yè) > 抗體 > 兔單抗 > ErbB-3 (Phospho Tyr1289) Rabbit mAb
ErbB-3 (Phospho Tyr1289) Rabbit mAb
商品貨號(hào)： PRM8714
適 應(yīng) 性： 人,小鼠,大鼠
WB IHC IF ELISA IP
￥7000元
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商品描述
  • 發(fā)貨日期： 現(xiàn)貨
  • 靶點(diǎn)-Target： ErbB-3/her2
  • 反應(yīng)性-Reactivity： 人,小鼠,大鼠
  • 應(yīng)用-Applications： WB,IHC,IF,IP,ELISA
  • MW(Calculated)： 148kD
  • MW(Observed)： 185kD
  • 宿主物種-Host Species： Rabbit
  • 同種型-Isotype： IgG, Kappa
  • 偶聯(lián)-Conjugate： Phospho
  • 修飾-Modification： Tyr1289
  • 推薦稀釋比： IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
  • 組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • 純化工藝： Protein A
  • 儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 克隆號(hào)： PT0990R
  • 特異性： Phospho-ErbB-3 (Y1289) Monoclonal Antibody detects endogenous levels of ErbB-3 protein only when phosphorylated at Y1289.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):QGyEE
  • 基因名稱(chēng)： ERBB3
  • 蛋白名稱(chēng)： Receptor tyrosine-protein kinase erbB-3
  • 別名： ERBB3;HER3;Receptor tyrosine-protein kinase erbB-3;Proto-oncogene-like protein c-ErbB-3;Tyrosine kinase-type cell surface receptor HER3
  • Organism-1： Human
  • 基因ID-1： 2065
  • SwissProt-1： P21860
  • Organism-2： Mouse
  • 基因ID-2： 13867
  • SwissProt-2： Q61526
  • Organism-3： Rat
  • 基因ID-3： 29496
  • SwissProt-3： Q62799
  • 背景： This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers, including prostate, bladder, and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. One isoform lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the m
  • 細(xì)胞定位： [Isoform 1]: Cell membrane ; Single-pass type I membrane protein.; [Isoform 2]: Secreted.
ErbB-3 (Phospho Tyr1289) Rabbit mAb
Catalog No PRM8714
Product information
  • 發(fā)貨日期： 現(xiàn)貨
  • 靶點(diǎn)-Target： ErbB-3/her2
  • 反應(yīng)性-Reactivity： 人,小鼠,大鼠
  • 應(yīng)用-Applications： WB,IHC,IF,IP,ELISA
  • MW(Calculated)： 148kD
  • MW(Observed)： 185kD
  • 宿主物種-Host Species： Rabbit
  • 同種型-Isotype： IgG, Kappa
  • 偶聯(lián)-Conjugate： Phospho
  • 修飾-Modification： Tyr1289
  • 推薦稀釋比： IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
  • 組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • 純化工藝： Protein A
  • 儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 克隆號(hào)： PT0990R
  • 特異性： Phospho-ErbB-3 (Y1289) Monoclonal Antibody detects endogenous levels of ErbB-3 protein only when phosphorylated at Y1289.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):QGyEE
  • 基因名稱(chēng)： ERBB3
  • 蛋白名稱(chēng)： Receptor tyrosine-protein kinase erbB-3
  • 別名： ERBB3;HER3;Receptor tyrosine-protein kinase erbB-3;Proto-oncogene-like protein c-ErbB-3;Tyrosine kinase-type cell surface receptor HER3
  • Organism-1： Human
  • 基因ID-1： 2065
  • SwissProt-1： P21860
  • Organism-2： Mouse
  • 基因ID-2： 13867
  • SwissProt-2： Q61526
  • Organism-3： Rat
  • 基因ID-3： 29496
  • SwissProt-3： Q62799
  • 背景： This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers, including prostate, bladder, and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. One isoform lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the m
  • 細(xì)胞定位： [Isoform 1]: Cell membrane ; Single-pass type I membrane protein.; [Isoform 2]: Secreted.
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