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首頁 > 細胞 > 人源細胞系 > 人卵巢腺癌細胞(OVCAR3)
人卵巢腺癌細胞(OVCAR3)
￥800.00元
細胞貨號： CL0373
細胞種屬： 人源細胞系
細胞別名： Ovcar-3; OVCAR 3; OVCAR.3; NIH:OVCAR-3; NIH:Ovcar-3; NIH:OVCAR3; NIH-OVCAR-3; NIHOVCAR3; OVCAR3; Ovcar3
發貨規格： 1×10?
供體信息： 60歲白人女性
腫瘤類型： 高級別卵巢漿液性腺癌
組織來源： 卵巢
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背景信息
  • 種屬： 人源細胞系
  • 組織來源： 卵巢
  • 腫瘤類型： 高級別卵巢漿液性腺癌
  • 供體信息： 60歲白人女性
  • 背景描述： OVCAR-3 細胞是由一名 60 歲白種人女性卵巢進行性腺癌患者的惡性腹水建立的人類卵巢癌細胞系，對環磷酰胺、阿霉素和順鉑治療無效。Ovcar 3 細胞用于廣泛的研究，包括耐藥性，特別是涉及 DNA 損傷反應生物標志物、同源重組修復以及整體細胞周期動力學、癌細胞生物學和基因表達研究的研究。 OVCAR-3細胞其特征在于其高體外生長潛力和在免疫缺陷小鼠中形成腫瘤的能力。這些細胞表達卵巢癌的幾種特征標志物，并已被廣泛用于研究卵巢癌的生物學。
培養建議
  • 生長形態： 上皮細胞樣
  • 生長特性： 貼壁
  • 培養條件： RPMI-1640+20%FBS+1%P/S+0.01mg/ml牛胰島素
  • 凍存條件： 90%FBS+10%DMSO
  • 血清使用等級： 標準
  • 傳代方式： 胰酶消化
  • 倍增時間： 35~64h
  • 傳代比例： 胰酶消化
  • 換液頻率： 每周2~3次
  • 生物安全等級： 1
  • 培養注意事項：
其他信息
  • 受體表達： Androgen, estrogen, progesterone，Androgen receptor, positive; estrogen receptor, positive; progesterone receptor, positive
  • 同工酶： G6PD, B, PGM1, 1, PGM3, 1, ES-D, 1, AK-1, 1, GLO-1, 1
  • 致瘤性： Yes, in nude mice
  • 核型： The cell line is aneuploid human female, with chromosome counts in the sub to near-triploid range. Several normal chromosomes (N11, N13, N14, N15, N16, N17, and N22) are clearly under-represented. Many of these missing chromosomes are represented in the large number of cytogenetically altered chromosomes identified as marker chromosomes. In addition to the marker chromosomes, there are a large number of other structurally abnormal and unassignable chromosomes that are not recognized as markers. Random loss and gain of chromosomes from cell to cell are noted in the exact chromosome counts and in the analysis of the karyotypes.
人卵巢腺癌細胞
Catalog No CL0373
Product information
  • 受體表達： Androgen, estrogen, progesterone，Androgen receptor, positive; estrogen receptor, positive; progesterone receptor, positive
  • 同工酶： G6PD, B, PGM1, 1, PGM3, 1, ES-D, 1, AK-1, 1, GLO-1, 1
  • 致瘤性： Yes, in nude mice
  • 核型： The cell line is aneuploid human female, with chromosome counts in the sub to near-triploid range. Several normal chromosomes (N11, N13, N14, N15, N16, N17, and N22) are clearly under-represented. Many of these missing chromosomes are represented in the large number of cytogenetically altered chromosomes identified as marker chromosomes. In addition to the marker chromosomes, there are a large number of other structurally abnormal and unassignable chromosomes that are not recognized as markers. Random loss and gain of chromosomes from cell to cell are noted in the exact chromosome counts and in the analysis of the karyotypes.
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